# Molecular basis of action potential
selectivity filter: select ions
activation gate
记录单个通道的电流?原理是什么
open probability? 类比作原子的衰变?布朗运动
single channel conductance: 通道打开时的电流(电化学力一定时)
神经元上的离子通道密度是不同的
密度越大,threshold 越小(Na+)
passive: how signal decays
2 kinds of resistance
- membrane resistance (changed by the gating of ion channel)
- internal resistance (Constant)