# Molecular basis of action potential

selectivity filter: select ions

activation gate

记录单个通道的电流?原理是什么

open probability? 类比作原子的衰变?布朗运动

single channel conductance: 通道打开时的电流(电化学力一定时)

神经元上的离子通道密度是不同的

密度越大,threshold 越小(Na+)

passive: how signal decays

2 kinds of resistance

  • membrane resistance (changed by the gating of ion channel)
  • internal resistance (Constant)

# Synapses